Buy IDRA-21 Powder Online | Certified Analytical Reference Materials
Optimize your laboratory’s glutamatergic pathway mapping and cognitive-pharmacology reference indexing with high-purity, uniform chemical arrays. Premium-grade IDRA-21 (7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide) Analytical Reference Powder is now in stock and available for immediate procurement across global research networks from Strem Chemicals.
IDRA-21 is a highly potent, synthetic ampakine molecule belonging to the benzothiadiazine chemical class. As a positive allosteric modulator ($PAM$) of the $\alpha$-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor, it binds to specific regulatory sites to attenuate receptor desensitization and deactivation. This precise mechanism prolongs excitatory synaptic currents and promotes long-term potentiation ($LTP$) in neuronal modeling pathways. The bulk crystalline powder format serves as an uncompromised, high-purity standard critical for establishing quantitative calibration curves, method validation protocols, and mass spectrometry fragmentation profiles ($GC/MS$ or $LC/MS/MS$).
This certified reference material provides an essential tool for neuropharmacologists and forensic toxicologists conducting investigative assays or tracking novel cognitive-enhancing agents. Explore our full catalog to find matching pure standards and analytical laboratory reagents for your institution.
Notice: This product is strictly intended for scientific research and forensic applications. It is not under any circumstances approved for human or veterinary consumption.
The Strem Chemicals Quality Advantage
In high-precision quantitative analysis, forensic profiling, and toxicological benchmarking, resolving active targets requires absolute uniformity and protection against sample degradation. Sourcing your reference materials from Strem Chemicals provides key operational advantages:
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Batch-Verified Chemical Purity: Every production lot undergoes extensive independent laboratory validation (including HPLC, GC-MS, and NMR spectroscopy) to confirm structural identity and guarantee an uncompromised purity profile exceeding 98%.
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Atmospheric Shielding & Integrity: Dispatched in premium, light-shielding, moisture-controlled secure containers to isolate the benzothiadiazine molecules from ambient light, humidity, and atmospheric degradation during transit.
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Consistent Crystalline Baseline: Produced as a fine white to off-white crystalline powder that features excellent solubility parameters in dimethyl sulfoxide (DMSO) and ethanol, allowing immediate integration into assay buffers.
Technical & Analytical Profile
| Parameter | Specification |
| Active Target Compound | IDRA-21 |
| IUPAC Name | 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide |
| Molecular Formula | $C_{8}H_{9}ClN_{2}O_{2}S$ |
| Molecular Weight | 232.69 g/mol |
| Chemical Classification | Ampakine / Benzothiadiazine Derivative |
| Format | Fine crystalline analytical reference powder |
| Purity Tier | Ultra-Pure Analytical Grade ($\ge$98% HPLC verified) |
| Primary Research Scope | AMPA receptor allosteric modulation, synaptic plasticity assays, instrument calibration ($HPLC$, $LC-MS/MS$) |
| Documentation Inclusions | Batch-specific COA, independent spectral validation, and safety data sheets |
The structural traits of our analytical units provide excellent shelf-life stability and predictable degradation resistance, maintaining molecular integrity for up to 24 months when stored under ideal climate-controlled conditions.
Laboratory Safety & Regulatory Guidelines
Mandatory Compliance Notice: IDRA-21 Analytical Reference Powder is developed, manufactured, and distributed exclusively for professional in vitro laboratory research, chemical profiling, and forensic identification standards. Under no circumstances is this compound approved for human consumption, clinical trials, or veterinary applications.
Because potent positive allosteric modulators exhibit strong biological activity within central neurotransmitter pathways, strict laboratory biosafety measures must be maintained:
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Wear Full PPE: Always utilize standard laboratory personal protective equipment, including chemical-resistant nitrile gloves, protective eyewear, and an approved laboratory coat during manipulation.
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Safe Handling Protocols: When measuring the crystalline powder for solutions or assay preparations, handle inside a certified chemical fume hood or well-ventilated enclosure to prevent accidental inhalation, cross-contamination, or particle dispersion.
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Verify Local Compliance: Buyers must be qualified researchers or licensed institutions with the appropriate credentials. Ensure your facility complies with all local, state, and national regulatory frameworks governing the importation, handling, and analysis of synthetic ampakine compounds and laboratory reference reagents.
Secure Premium Reference Standards Today
Do not risk your laboratory’s timeline, funding, or data integrity on unverified third-party web vendors. Partner with an established global industry authority recognized for unwavering quality assurance.
Buy IDRA-21 powder online from Strem Chemicals today and achieve flawless precision in your upcoming scientific investigations.





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